Variability of FEV1 and Criterion for Acute Pulmonary Exacerbation

Frontiers in Pediatrics

Bradlee A. Jenkins¹ 

关键词: cystic fibrosis;    functional expiratory volume;    pulmonary;    spirometry;    prognosis;    epidemiology;    adolescents;    Pseudomonas aeruginosa;   

DOI  :  10.3389/fped.2014.00114

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Morgan et al. (1) concluded that cystic fibrosis (CF) in children and adolescents with a high baseline forced expiratory volume (FEV1) were less likely to have a therapeutic intervention or slower rate of FEV1 decline after a single acute decline in FEV1 of 10%. This conclusion is not well supported due to the arbitrary criteria used for defining a pulmonary exacerbation, as explained below.

【 授权许可】

CC BY