Ophthalmic consequences of viral hemorrhagic fevers: Insights from the clinic and laboratory

Frontiers in Tropical Diseases

Tropical Diseases

Santi Karnam¹  Nam Nguyen²  Ye Huang²  Steven Yeh³ 

[1] Center for Academic Global Ophthalmology, Wills Eye Hospital, Philadelphia, PA, United States;Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United States;Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, United States;Global Center for Health Security, University of Nebraska Medical Center, Omaha, NE, United States;Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States;

关键词: viral hemorrhagic fever;    viral uveitis;    viral conjunctivitis;    emerging viral diseases;    yellow fever;    Ebola virus;    Lassa fever;   

DOI  :  10.3389/fitd.2023.1107786

 received in 2022-11-25, accepted in 2023-02-22,  发布年份 2023

来源: Frontiers

【 摘 要 】

Viral hemorrhagic fevers (VHFs) are a diverse group of RNA virus-mediated systemic diseases with significant morbidity and mortality and represent a significant public health concern. Given the high systemic morbidity and mortality in a number of these entities, delays in diagnosis can lead to downstream public health consequences. Many viral hemorrhagic fevers have ophthalmic manifestations and ophthalmologists thus play a key role in disease recognition and the management of ocular complications associated with specific hemorrhagic fevers. This review summarizes the key ophthalmic consequences of viral hemorrhagic fevers, viral disease pathogenesis, disease findings, and areas of unmet research need.

【 授权许可】

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Copyright © 2023 Karnam, Huang, Nguyen and Yeh