Raman and fourier transform infrared spectroscopy techniques for detection of coronavirus (COVID-19): a mini review

Frontiers in Chemistry

Chemistry

Xiaoru Zhang¹  Guoliang Qi²  Cheng Tian²  Lei Zhao²  Qiuqi Zhang³ 

[1] Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis and College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, China;Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, Collaborative Innovation Center of Tumor Marker Detection Technology, Equipment and Diagnosis-Therapy Integration in Universities of Shandong, College of Chemistry and Chemical Engineering, Linyi University, Linyi, China;The First School of Clinical Medicine, Southern Medical University, Guangzhou, China;

关键词: COVID-19;    diagnostics;    Raman spectroscopy;    FTIR spectroscopy;    SERS;    ATR-FTIR;   

DOI  :  10.3389/fchem.2023.1193030

 received in 2023-03-24, accepted in 2023-05-01,  发布年份 2023

来源: Frontiers

【 摘 要 】

Coronavirus pandemic has been a huge jeopardy to human health in various systems since it outbroke, early detection and prevention of further escalation has become a priority. The current popular approach is to collect samples using the nasopharyngeal swab method and then test for RNA using the real-time polymerase chain reaction, which suffers from false-positive results and a longer diagnostic time scale. Alternatively, various optical techniques, namely, optical sensing, spectroscopy, and imaging shows a great promise in virus detection. In this mini review, we briefly summarize the development progress of vibrational spectroscopy techniques and its applications in the detection of SARS-CoV family. Vibrational spectroscopy techniques such as Raman spectroscopy and infrared spectroscopy received increasing appreciation in bio-analysis for their speediness, accuracy and cost-effectiveness in detection of SARS-CoV. Further, an account of emerging photonics technologies of SARS-CoV-2 detection and future possibilities is also explained. The progress in the field of vibrational spectroscopy techniques for virus detection unambiguously show a great promise in the development of rapid photonics-based devices for COVID-19 detection.

【 授权许可】

Unknown   
Copyright © 2023 Zhang, Zhao, Qi, Zhang and Tian.