Associations between cognition, anxiety, depression, and residual dizziness in elderly people with BPPV

Frontiers in Aging Neuroscience

Neuroscience

Xiaobao Ma¹  Ying Yang¹  Jiali Shen¹  Xiangping Chen¹  Yulian Jin¹  Jianyong Chen¹  Jun Yang¹  Kuan He¹  Lu Wang¹  Jin Sun¹  Wei Wang¹ 

[1] Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China;Shanghai Jiao Tong University School of Medicine Ear Institute, Shanghai, China;Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases, Shanghai, China;

关键词: elderly;    BPPV;    residual dizziness;    anxiety;    depression;    cognition;    vertigo;   

DOI  :  10.3389/fnagi.2023.1208661

 received in 2023-04-19, accepted in 2023-08-17,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveTo investigate the associations between cognition, anxiety, depression, and residual dizziness after successful repositioning maneuvers in the elderly with benign paroxysmal positional vertigo (BPPV).MethodsWe enrolled 40 elderly patients with BPPV in our outpatient department. We used the Dizziness Handicap Inventory (DHI), Visual Analog Scale (VAS), Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder Questionnaire-7 (GAD-7) to assess the degree of dizziness, anxiety, and depression of participants before repositioning therapy, respectively. At the 1-week follow-up after BPPV treatment, each participant will be reassessed and divided into a group with residual dizziness (RD) and a group without residual dizziness (NRD) based on the follow-up DHI score. The Mini-Mental State Examination (MMSE) evaluated the cognitive function of the participants.ResultsThe age, gender, duration of BPPV, and involved semicircular canals in the two groups did not show a significant difference. The RD group scored significantly higher on the DHI (p = 0.006), GAD-7 (p < 0.001), and PHQ-9 (p = 0.002) before the repositioning treatment than the NRD group. The two groups had no significant difference in MMSE score (p = 0.381). Anxiety and depression scores before repositioning treatment significantly and positively correlated with follow-up DHI scores (r = 0.678 and 0.522, respectively), but the MMSE score did not significantly relate to it. The univariate linear regression showed that the DHI (p < 0.001), GAD-7 (p < 0.001), and PHQ-9 (p = 0.002) scores before treatment could predict residual dizziness. The multivariate linear regression showed that GAD-7 before treatment was the only significant predictor of residual dizziness (p < 0.001).ConclusionThe level of dizziness, anxiety, and depression before treatment can predict residual dizziness after successful repositioning maneuvers in the elderly with BPPV. Anxiety may be the strongest predictor of residual dizziness after successful repositioning treatment in elderly BPPV patients.

【 授权许可】

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Copyright © 2023 Sun, Ma, Yang, He, Wang, Shen, Wang, Chen, Jin, Yang and Chen.