Epidemiological, clinical, therapeutic features and predictors of death among COVID-19 patients hospitalized in Parakou: a cross-sectional study in Northern Benin

BMC Infectious Diseases

Research

Klikpezo Roger¹  Mama Cissé Ibrahim¹  Savi de Tovè Kofi-Mensa²  Codjo Léopold²  Adé Serge²  Yamongbè Clodel³  Attinsounon Cossi Angelo⁴  Attinon Julien⁵ 

[1] Faculty of Medicine, University of Parakou, 03 P.O Box 112, Parakou, Benin;Regional Care Center of COVID-19 Cases of Parakou, Parakou, Benin;Regional Military Hospital of Parakou, Parakou, Benin;Faculty of Medicine, University of Parakou, 03 P.O Box 112, Parakou, Benin;Regional Teaching Hospital of Borgou, Parakou, Benin;Regional Care Center of COVID-19 Cases of Parakou, Parakou, Benin;Infectious Diseases and Tropical Medicine Unit, Parakou, Benin;Faculty of Medicine, University of Parakou, 03 P.O Box 112, Parakou, Benin;Regional Teaching Hospital of Borgou, Parakou, Benin;Infectious Diseases and Tropical Medicine Unit, Parakou, Benin;Faculty of Medicine, University of Parakou, 03 P.O Box 112, Parakou, Benin;Regional Teaching Hospital of Borgou, Parakou, Benin;Regional Care Center of COVID-19 Cases of Parakou, Parakou, Benin;Regional Care Center of COVID-19 Cases of Parakou, Parakou, Benin;Regional Military Hospital of Parakou, Parakou, Benin;

关键词: COVID-19;    Epidemiology;    Clinical features;    Therapy;    Prognosis;    Parakou;    Benin;   

DOI  :  10.1186/s12879-023-08445-z

 received in 2023-04-21, accepted in 2023-07-05,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundCOVID-19 is an emerging contagious infection with polymorphic clinical manifestations. The purpose of this study was to describe the epidemiological, clinical, therapeutic features and identify the predictors of mortality among COVID-19 hospitalized cases in Parakou.MethodsThis was a cross-sectional, descriptive and analytic study. Systematic recruitment was used to include all patients hospitalized with COVID-19 from May 8, 2020, to December 31, 2021, whose medical records were available and usable. The variables studied were clinical and paraclinical signs, diagnostic and therapeutic means, evolution under treatment and prognostic factors. This study was approved by the Local Ethical Committee. The data were analyzed using Stata/MP 14.1 software.ResultsA total of 198 cases of COVID-19 were identified, 117 of whom were men. The mean age was 51.53 ± 19.51 years. The presenting signs were fever 146 (74.11%), cough 157 (79.70%) and dyspnea 118 (53.90%). It was severe COVID-19 in 108 cases (54.55%). Therapeutically, 95 patients (47.98%) had received the combination of Lopinavir/ritonavir and Ribavirin and 95 others (47.98%) received chloroquine. Recovery was noted in 151 (76.26%) patients. Mortality rate was 18.18%. Predictors of death were high blood pressure, presence of signs of severity, high-concentration mask ventilation used, and elevated transaminases.ConclusionCOVID-19 was a reality in Parakou, with a significant number of severe cases requiring hospitalization. Several factors are associated with the prognosis of the disease.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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Fig. 5