Validation of a new simple scoring system to predict spontaneous bacterial peritonitis in patients with cirrhosis and ascites

BMC Gastroenterology

Research

Ngoc Cao Huynh¹  Thong Duy Vo² 

[1]Department of Gastroenterology, Cho Ray Hospital, 217 Hong Bang, Ward 11, Dis. 5, 72714, Ho Chi Minh, Vietnam

[2]Department of Gastroenterology, Cho Ray Hospital, 217 Hong Bang, Ward 11, Dis. 5, 72714, Ho Chi Minh, Vietnam

[3]Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam

关键词: Spontaneous bacterial peritonitis;    Ascites;    Cirrhosis;    Predictors;    Mansoura scoring system;   

DOI  :  10.1186/s12876-023-02919-9

 received in 2023-04-04, accepted in 2023-08-07,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundRecently, a simple scoring system named the Mansoura scoring system was developed to predict spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and ascites. However, the efficacy of this newly developed system has not been extensively investigated. We aimed to validate a new simple scoring system for the rapid diagnosis or exclusion of SBP without paracentesis.MethodsAdult patients with cirrhosis and ascites admitted to Cho Ray Hospital between November 2021 and May 2022 were included. The area under the receiver operating characteristic (AUROC) curve of the Mansoura simple scoring system for predicting SBP was calculated using the Stata software. Other independent laboratory tests for predicting SBP (C-reactive protein [CRP], neutrophil-to-lymphocyte ratio [NLR], and mean platelet volume [MPV]) were assessed and compared using the Mansoura scoring system.ResultsA total of 121 patients were included in this study. The Mansoura scoring system showed good performance in predicting SBP in patients with cirrhosis and ascites (AUROC:0.89). At the cut-off ≥ 4 points, the scoring system achieved a specificity of 97.7% with a positive predictive value for the diagnosis of SBP of 93.5%. Multivariate analysis was performed using our data and showed that NLR, CRP level, and MPV were independent factors related to SBP.ConclusionThe Mansoura scoring system demonstrated good performance in predicting SBP in patients with cirrhosis and ascites and may help guide management decisions.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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