期刊论文详细信息
Thyroid Research
Clinicopathological profile and management of thyroid carcinoma: a Sub-Saharan country experience
Research
Areeg Faggad1  Moawia Mohammed Ali Elhassan2  Mohamed Dafalla Awadalla Gismalla3  Sahar Abdelrahman Hamid Mohamed4 
[1] Department of Molecular Biology, National Cancer Institute – University of Gezira, Wad Medani, Sudan;Department of Oncology, National Cancer Institute – University of Gezira, Wad Medani, Sudan;Department of Surgery, Faculty of Medicine, University of Gezira, Wad Medani, Sudan;Ministry of Health, Gezira State, Wad Medani, Sudan;
关键词: Thyroid cancer;    Follicular carcinoma;    Anaplastic carcinoma;    Goiter;    Radioactive iodine;    Sudan;   
DOI  :  10.1186/s13044-023-00173-5
 received in 2022-12-11, accepted in 2023-07-18,  发布年份 2023
来源: Springer
PDF
【 摘 要 】

BackgroundIn Sudan, there is limited knowledge on the epidemiology, clinical characteristics and pathological patterns of thyroid cancer. To address this shortcoming, we studied the clinical, pathological and treatment patterns of thyroid cancer at the National Cancer Institute ‒ University of Gezira (NCI-UG), Sudan.MethodsWe performed a retrospective health facility–based study of patients with thyroid cancer who were treated at NCI–UG from January 2009 to December 2017.ResultsA total of 139 patients with thyroid cancer were identified during the study period. Tumors were more common among women (69%). Goiter was the main presenting symptom (85%). The most common type of thyroid cancer was follicular carcinoma (41%), followed by papillary carcinoma (24%), then anaplastic carcinoma (20%). The mean age of the women was 56.3 years (SD ± 14.7), compared to 52.5 years (SD ± 16.6) for the men. The frequencies of stage I, II, III, and IV were 17%, 22%, 16%, and 45%, respectively. Different types of thyroidectomies were performed in 79% of the cases, lobectomy in 4%, and no surgery in 17%. Only 28% of the cases received radioactive iodine. Palliative chemotherapy and radiotherapy were prescribed to 17% and 37% of the cases, respectively.ConclusionThyroid cancer is more prevalent among women and most patients present at later stages. The dominance of follicular type suggests that the majority of this population is iodine-deficient.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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