Exploring patient treatment decision making for osteoarthritis in the UAE: a cross-sectional adaptive choice-based conjoint study

BMC Public Health

Research

Basem Al-Omari¹  Joviana Farhat¹  Abdulla Alrahoomi²  Hristo Grancharov²  Sammy Hanna³  Mumtaz Khan⁴  Zaki Abu Zahr⁵ 

[1] Department of Epidemiology and Population Health, College of Medicine and Health Sciences, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates;Department of Epidemiology and Population Health, College of Medicine and Health Sciences, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates;Department of Orthopedics & Sports Medicine, Healthpoint Hospital, P.O. Box 112308, Abu Dhabi, United Arab Emirates;Department of Epidemiology and Population Health, College of Medicine and Health Sciences, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates;Department of Orthopedics & Sports Medicine, Healthpoint Hospital, P.O. Box 112308, Abu Dhabi, United Arab Emirates;Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Whitechapel, E1 2AD, London, UK;Department of Epidemiology and Population Health, College of Medicine and Health Sciences, Khalifa University, P.O. Box 127788, Abu Dhabi, United Arab Emirates;Department of Rheumatology, Sheikh Shakhbout Medical City (SSMC), P.O. Box 11001, Abu Dhabi, United Arab Emirates;Department of Rheumatology, Healthpoint Hospital, P.O. Box 112308, Abu Dhabi, United Arab Emirates;

关键词: Osteoarthritis;    Patients’ preferences;    Adaptive choice-based conjoint;    Pharmaceutical treatment;    Web-based questionnaires;   

DOI  :  10.1186/s12889-023-16490-1

 received in 2023-02-24, accepted in 2023-08-09,  发布年份 2023

来源: Springer

【 摘 要 】

ObjectiveTo assess osteoarthritis (OA) patients’ preferences for pharmaceutical treatment via Adaptive Choice-Based Conjoint (ACBC) method.MethodsA United Arab Emirates (UAE) based Patient and Public Involvement (PPI) group designed the ACBC questionnaire with 10 attributes and 34 levels. The questionnaire was developed using Sawtooth Software and analyzed through Hierarchical Bayesian (HB). Results were standardized using Z-score via SPSS.ResultsStudy participants were 1030 OA patients, 83.6% aged 50 or older and 83.4% female. The avoidance of medication’s side effects accounted for 66% relative importance compared to 6% relative importance for the medication’s benefits. The “way of taking the medicine” attribute had the highest coefficient of variation (70%) and the four side effect attributes “risk of gastric ulcer, addiction, kidney and liver impairment, and heart attacks and strokes” had a coefficient of variation from 18 to 21%.ConclusionsArab OA patients are similar to other ethnic groups in trading-off benefits and side effects and consistently prioritizing the avoidance of medications’ side effects. Although the “Way of taking medicine” was the least important attribute it was associated with the highest variation amongst patients. OA patients also prefer prescribed medications to internet-purchased and over-the-counter options.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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