Minimal change disease with papillary thyroid carcinoma: a report of two adult cases

BMC Nephrology

Case Report

Zedong Hao¹  Weimin Yu²  Juanjuan Yin²  Xiaojun Ren²  Zexuan Li²  Zhuanzhuan Yu³  Guang Yang⁴ 

[1] Department of General Surgery, the First People’s Hospital of Jinzhong, 030699, Jinzhong, China;Department of Nephrology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, 030032, Taiyuan, China;Department of Pathology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 030032, Taiyuan, China;Taiyuan Kingmed Clinical Laboratory Co., Ltd, Taiyuan, China;

关键词: Papillary thyroid carcinoma;    Hypothyroidism;    Nephrotic syndrome;    Minimal change disease;   

DOI  :  10.1186/s12882-023-03252-9

 received in 2023-03-27, accepted in 2023-06-21,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundMinimal change disease (MCD), a pathological type of nephrotic syndrome (NS), can occur in patients with tumors. We report two adult cases of MCD associated with papillary thyroid carcinoma (PTC), known to be extremely rare in adults.Case presentationA 35-year-old female patient was simultaneously diagnosed with MCD and PTC. The MCD was effectively treated with thyroidectomy and prednisone.In addition, a 50-year-old male patient, who had been diagnosed with PTC three years prior, had MCD confirmed by renal biopsy. The patient achieved complete remission following treatment with tacrolimus and rituximab.ConclusionsThe present case report describes and discusses the diagnostic and treatment processes employed in these two patients. Clinicians need to be aware of the renal effects of treating patients with solid tumors.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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