The Full Value of Vaccine Assessments (FVVA): a framework for assessing and communicating the value of vaccines for investment and introduction decision-making

BMC Medicine

Correspondence

Mark Jit¹  So Yoon Sim²  Siobhan Botwright²  Birgitte Giersing²  Raymond Hutubessy²  David Kaslow³  Jeremy A. Lauer⁴ 

[1]Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK

[2]Immunization, Vaccines and Biologicals Department, World Health Organization, 20 Avenue Appia, CH-1211, Geneva, Switzerland

[3]PATH Center for Vaccine Innovation and Access, Seattle, USA

[4]Strathclyde Business School, University of Strathclyde, Glasgow, UK

关键词: Vaccines;    Immunization;    Research and development;    Public health;    Economic evaluations;    Health technology assessment;   

DOI  :  10.1186/s12916-023-02929-0

 received in 2022-10-18, accepted in 2023-06-08,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundSeveral economic obstacles can deter the development and use of vaccines. This can lead to limited product options for some diseases, delays in new product development, and inequitable access to vaccines. Although seemingly distinct, these obstacles are actually interrelated and therefore need to be addressed through a single over-arching strategy encompassing all stakeholders.MethodsTo help overcome these obstacles, we propose a new approach, the Full Value of Vaccines Assessments (FVVA) framework, to guide the assessment and communication of the value of a vaccine. The FVVA framework is designed to facilitate alignment across key stakeholders and to enhance decision-making around investment in vaccine development, policy-making, procurement, and introduction, particularly for vaccines intended for use in low- and middle-income countries.ResultsThe FVVA framework has three key elements. First, to enhance assessment, existing value-assessment methods and tools are adapted to include broader benefits of vaccines as well as opportunity costs borne by stakeholders. Second, to improve decision-making, a deliberative process is required to recognize the agency of stakeholders and to ensure country ownership of decision-making and priority setting. Third, the FVVA framework provides a consistent and evidence-based approach that facilitates communication about the full value of vaccines, helping to enhance alignment and coordination across diverse stakeholders.ConclusionsThe FVVA framework provides guidance for stakeholders organizing global-level efforts to promote investment in vaccines that are priorities for LMICs. By providing a more holistic view of the benefits of vaccines, its application also has the potential to encourage greater take-up by countries, thereby leading to more sustainable and equitable impacts of vaccines and immunization programmes.

【 授权许可】

CC BY   
© The Author(s) 2023

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