Shining the Light on Astrocytic Ensembles

卷:12

Review

关键词: TRANSLATIONAL PROFILING APPROACH;    IN-VIVO;    3-DIMENSIONAL RELATIONSHIPS;    PROTOPLASMIC ASTROCYTES;    FUNCTIONAL PLASTICITY;    STRUCTURAL PLASTICITY;    CULTURED ASTROCYTES;    CORTICAL ASTROCYTES;    CALCIUM TRANSIENTS;    NEURONAL-ACTIVITY;   

DOI  :  10.3390/cells12091253

来源: SCIE

【 摘 要 】

While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute significantly to animal conduct and suggest that studying the maps of these ensembles in conjunction with neurons is crucial for a more comprehensive understanding of behavior. We also discuss available methods for studying astrocytes and argue that these ensembles, complementarily with neurons, code and integrate complex behaviors, potentially specializing in concrete functions.