The compact genome of the sponge Oopsacas minuta (Hexactinellida) is lacking key metazoan core genes

BMC Biology

Research Article

Caroline Rocher¹  Carole Borchiellini¹  Marjorie Selva¹  Emmanuelle Renard²  Quentin Schenkelaars³  André Le Bivic⁴  Laurent Kodjabachian⁵  Hassiba Belahbib⁶  Sébastien Santini⁶  Jean-Michel Claverie⁶  Cyril Jourda⁷  Ana Riesgo⁸  Marc Duchesne⁹  Sally P. Leys⁹  Michel Vervoort^1,10 

[1]Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, Marseille, France

[2]Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, Marseille, France

[3]Aix Marseille Univ, CNRS, IBDM, UMR 7288, Marseille, France

[4]Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, Marseille, France

[5]Institut Jacques Monod, CNRS, UMR 7592, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France

[6]Aix Marseille Univ, CNRS, IBDM, UMR 7288, Marseille, France

[7]Aix Marseille Univ, CNRS, IBDM, UMR 7288, Turing Center for Living Systems, Marseille, France

[8]Aix Marseille Univ, CNRS, IGS, UMR 7256, IMM, IM2B, IOM, Marseille, France

[9]Aix Marseille Univ, CNRS, IGS, UMR 7256, IMM, IM2B, IOM, Marseille, France

[10]CIRAD, UMR PVBMT, La Réunion, France

[11]Department of Biodiversity and Evolutionary Biology, Madrid, Spain

[12]Department of Life Sciences, Natural History Museum of London, SW7 5BD, London, UK

[13]Department of Biological Sciences, University of Alberta, T6G 2E9, Edmonton, AB, Canada

[14]Institut Jacques Monod, CNRS, UMR 7592, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France

关键词: Microbiome;    Symbiosis;    Epithelium;    Ciliogenesis;    Signaling pathways;    Transcription factors;    Photoreception;    Signal transduction;    Skeleton;    Silicification;   

DOI  :  10.1186/s12915-023-01619-w

 received in 2022-09-02, accepted in 2023-05-09,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundExplaining the emergence of the hallmarks of bilaterians is a central focus of evolutionary developmental biology—evodevo—and evolutionary genomics. For this purpose, we must both expand and also refine our knowledge of non-bilaterian genomes, especially by studying early branching animals, in particular those in the metazoan phylum Porifera.ResultsWe present a comprehensive analysis of the first whole genome of a glass sponge, Oopsacas minuta, a member of the Hexactinellida. Studying this class of sponge is evolutionary relevant because it differs from the three other Porifera classes in terms of development, tissue organization, ecology, and physiology. Although O. minuta does not exhibit drastic body simplifications, its genome is among the smallest of animal genomes sequenced so far, and surprisingly lacks several metazoan core genes (including Wnt and several key transcription factors). Our study also provides the complete genome of a symbiotic Archaea dominating the associated microbial community: a new Thaumarchaeota species.ConclusionsThe genome of the glass sponge O. minuta differs from all other available sponge genomes by its compactness and smaller number of encoded proteins. The unexpected loss of numerous genes previously considered ancestral and pivotal for metazoan morphogenetic processes most likely reflects the peculiar syncytial tissue organization in this group. Our work further documents the importance of convergence during animal evolution, with multiple convergent evolution of septate-like junctions, electrical-signaling and multiciliated cells in metazoans.

【 授权许可】

CC BY   
© The Author(s) 2023

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