期刊论文详细信息
Basic and Clinical Andrology
Long-term effect of sleeve gastrectomy surgery on Hormonal Profile, Semen Parameters and sexual functions of obese infertile men; a prospective observational study
Research Article
Ahmed F. El-sherbeiny1  Mohamed Amer2  Hamdy Farag3  Tamer Saafan4  Mohamed A. Hussein5  Khalid Kutub6  Mohamed Zamra7  Eman M. El-dydamony8  Ayman K. Koritenah8  Osama Shalkamy8  Osama M. Ghoneimy8  Mohamed A. Abdelaal8  Tamer A. Abouelgreed8  Adel Elatreisy8  Sherin A. Hefny9  Eman H. Ibrahim1,10 
[1] Department of Andrology, International Islamic Center for Population Study and Research, Al-Azhar University, Cairo, Egypt;Department of Dermatology and Andrology, Al-Azhar University, Cairo, Egypt;Department of Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt;Department of Surgery, Gulf Medical University, Ajman, UAE;Department of Surgery, Saudi German Hospital, Ajman, UAE;Department of Urology, Al sharq hospital, Fujairah, UAE;Department of Urology, AlQasemi Hospital, Sharjah, UAE;Department of Urology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt;Department of clinical Pathology, Ministry of Health and Prevention, Dubai, UAE;Gulf Medical University, P.O. Box 11117, Ajman, UAE;Department of Pathology, Faculty of medicine, Al-Azhar University, Cairo, Egypt;
关键词: Obesity;    Semen parameters;    Sleeve gastrectomy;    Obésité;    Paramètres du Sperme;    Gastrectomie longitudinale;    Sleeve Gastrectomie;   
DOI  :  10.1186/s12610-023-00191-1
 received in 2022-11-19, accepted in 2023-03-01,  发布年份 2023
来源: Springer
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【 摘 要 】

BackgroundThe effect of bariatric surgery on impaired semen parameters, hormonal profile and sexual function remains controversial to some extent.The context and purpose of the studyTo look at the long-term effects of sleeve gastrectomy on hormonal profiles, sperm parameters, and sexual function in infertile men with severe obesity. This prospective study included fifty-four obese patients with primary or secondary infertility who were scheduled for sleeve gastrectomy between February 2018 and March 2021. All participants were given a sperm analysis and a serum hormone profile before, 12, and 18 months after surgery. We used the International Index of Erectile Function questionnaire to assess sexual function.ResultsThere was a significant correlation between weight loss after sleeve gastrectomy and improvement in lipid profile (p < 0.05). No significant detectable effect of post-gastrectomy weight loss on patients with diabetes mellitus, hypertension, or obstructive sleep apnea. As regards the hormonal profile, sex hormone binding globulin, total and free testosterone improved significantly after 12- and 18-months following sleeve gastrectomy. There was a significant increase in sperm count and total sperm number during the follow-up after sleeve gastrectomy (p < 0.05), however, there were no significant changes in other semen parameters. Concerning sexual function, sexual desire, erectile function, and satisfaction improved significantly at 12 and 18 months after surgery.ConclusionWeight loss through sleeve gastrectomy surgery significantly improves testosterone deficiency, sexual performance, and Sperm count in obese infertile men.

【 授权许可】

CC BY   
© The Author(s) 2023

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