Prevalence and resistance profile of bacteria isolated from wound infections among a group of patients in upper Egypt: a descriptive cross-sectional study

BMC Research Notes

Research Note

Eman Farouk Ahmed¹  Gamal Fadl Mahmoud Gad²  Abdou M. A. Darwish³  Asia Helmi Rasmi⁴ 

[1] Assistant Professor of Microbiology and Immunology, Microbiology and Immunology Department, Faculty of Pharmacy, Sohag University, 82524, Province, Sohag, Egypt;Professor at Microbiology and Immunology, Microbiology and Immunology Department, Faculty of Pharmacy, Minia University, Elminya, Egypt;Professor of Plastic and Reconstructive Surgery, Plastic and Reconstructive Surgery Department, Faculty of Medicine, Minia University, Elminya, Egypt;Teaching assistant of Microbiology and Immunology, Microbiology and Immunology Department, Faculty of Pharmacy, Deraya University, Elminya, Egypt;

关键词: Egypt;    Prevalence;    Wound infection;    S. aureus;    P. aeruginosa;    MRSA;    MDR;   

DOI  :  10.1186/s13104-023-06379-y

 received in 2023-02-01, accepted in 2023-06-06,  发布年份 2023

来源: Springer

【 摘 要 】

AimThis cross-sectional survey aimed to identify aerobic bacteria, antimicrobial resistance, and multi-drug resistance profiles of bacteria isolated from different wound infections among a group of Egyptian patients.ResultsOf 120 positive samples, 170 isolates were identified. Polymicrobial infections were determined in 55% of samples. The dominant Gram-positive isolated strains were Staphylococcus aureus, especially from wound infections because of accidents (71.8%). Piperacillin, methicillin, ampicillin/sulbactam, and amoxicillin/clavulanic acid were all highly resistant to S. aureus and Coagulase-negative Staphylococci. The prevalence of methicillin-resistant S. aureus in wound infections was 89.9%. S. aureus showed superior sensitivity to vancomycin (85.3%) and linezolid (81.3%). The highest prevalence of Gram-negative isolates was for Pseudomonas aeruginosa (40%), which was highly sensitive to ciprofloxacin (79.2%) and highly resistant to levofloxacin (83.3%). Several isolates revealed a multi-drug resistance profile (52.4%). The overall MDR rate of Gram-positive and Gram-negative isolates were 50% and 54.9%, respectively.ConclusionThe prevalence of MRSA isolated from various wound infections and MDR is a warning issue in Upper Egypt. It should implement a health education strategy and hygiene measures to prevent the spread of wound infection-causing organisms in the community.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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Fig. 6