Genomics in animal breeding from the perspectives of matrices and molecules

Hereditas

Review

Martin Johnsson¹ 

[1] Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Box 7023, 75007, Uppsala, Sweden;

关键词: Genomics;    Animal breeding;    Genomic selection;    Gene editing;   

DOI  :  10.1186/s41065-023-00285-w

 received in 2023-01-12, accepted in 2023-05-03,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThis paper describes genomics from two perspectives that are in use in animal breeding and genetics: a statistical perspective concentrating on models for estimating breeding values, and a sequence perspective concentrating on the function of DNA molecules.Main bodyThis paper reviews the development of genomics in animal breeding and speculates on its future from these two perspectives. From the statistical perspective, genomic data are large sets of markers of ancestry; animal breeding makes use of them while remaining agnostic about their function. From the sequence perspective, genomic data are a source of causative variants; what animal breeding needs is to identify and make use of them.ConclusionThe statistical perspective, in the form of genomic selection, is the more applicable in contemporary breeding. Animal genomics researchers using from the sequence perspective are still working towards this the isolation of causative variants, equipped with new technologies but continuing a decades-long line of research.

【 授权许可】

CC BY   
© The Author(s) 2023. corrected publication 2023