Risk factors analysis of surgical complications of hepatic hemangioma: a modified Clavien-Dindo classification-based study

BMC Surgery

Research

Yan Ma¹  Yanling Yang²  Ruohan Zhang²  Wenjie Song²  Weigang Chen²  Zelong Yang²  Yong Chen²  Kai Yang²  Weihao Lv³  Hongyu Qiao⁴ 

[1] Department of Gynecology and Obstetrics, Xi Jing Hospital, Air Force Medical University, 710032, Xi’an, China;Department of Hepatobiliary Surgery, Xi Jing Hospital, Air Force Medical University, 710032, Xi’an, China;Department of Neurosurgery, Xi Jing Hospital, Air Force Medical University, 710032, Xi’an, China;Department of Pediatrics, Xi Jing Hospital, Air Force Medical University, 710032, Xi’an, China;

关键词: Hepatic hemangioma;    Surgery;    Clavien-Dindo classification;    Risk factor;    Complication;   

DOI  :  10.1186/s12893-023-02009-3

 received in 2023-02-16, accepted in 2023-04-16,  发布年份 2023

来源: Springer

【 摘 要 】

PurposeThere are few studies on the risk factors of postoperative complications after surgical treatment of hepatic hemangioma (HH). This study aims to provide a more scientific reference for clinical treatment.MethodsThe clinical characteristics and operation data of HH patients undergoing surgical treatment in the First Affiliated Hospital of Air Force Medical University from January 2011 to December 2020 were retrospectively collected. All enrolled patients were divided into two groups based on the modified Clavien-Dindo classification: Major group (Grade II/III/IV/V) and Minor group (Grade I and no complications). Univariate and multivariate regression analysis was used to explore the risk factors for massive intraoperative blood loss (IBL) and postoperative Grade II and above complications.ResultsA total of 596 patients were enrolled, with a median age of 46.0 years (range, 22–75 years). Patients with Grade II/III/IV/V complications were included in the Major group (n = 119, 20%), and patients with Grade I and no complications were included in the Minor group (n = 477, 80%). The results of multivariate analysis of Grade II/III/IV/V complications showed that operative duration, IBL, and tumor size increased the risk of Grade II/III/IV/V complications. Conversely, serum creatinine (sCRE) decreased the risk. The results of multivariate analysis of IBL showed that tumor size, surgical method, and operative duration increased the risk of IBL.ConclusionsOperative duration, IBL, tumor size, and surgical method are independent risk factors that should be paid attention to in HH surgery. In addition, as an independent protective factor for HH surgery, sCRE should attract more attention from scholars.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 13