Neurological features of COVID-19 and their treatment: a review

Drugs in Context

article

Daniele Orsucci¹  Elena Caldarazzo Ienco¹  Gianpaolo Nocita¹  Alessandro Napolitano¹  Marco Vista¹ 

[1] Unit of Neurology, San Luca Hospital

关键词: anosmia;    coronavirus;    COVID-19;    CPK;    Guillain–Barré syndrome;    myopathy;    myositis;    SARS-CoV-2;    Stroke;   

DOI  :  10.7573/dic.2020-5-1

学科分类：社会科学、人文和艺术（综合）

来源: C S F Medical Communications Ltd.

【 摘 要 】

Severe acute respiratory syndrome–correlated new coronavirus (SARS-Cov-2) infection may result in neurological signs and symptoms through different mechanisms. Although direct infection of the central nervous system is uncertain or very rare and the para-infectious complications (e.g. inflammatory neuropathies) are rare, delirium and septic encephalopathy are common in severely ill patients. Smell dysfunction and headache are very common in mild cases, especially in younger people and females. Muscle pain is common in both mild and severe cases, and in the most compromised patients, it is accompanied by increased creatine kinase levels and by a likely true myopathic damage. Ischemic stroke has been reported as a possible complication of the hypercoagulability associated with severe SARS-Cov-2 infection, but further studies are needed. Most of the neurological manifestations may occur early in the illness. Therefore, during the pandemic period, neurologists need to be involved, alert, and prepared. Neurological practice will not be the same until a vaccine is available.

【 授权许可】

CC BY-NC-ND