Numerical Simulation of Turbulent Blood Flow in the System of CoronaryArteries with Stenosis

Journal of Biometrics & Biostatistics

article

Mongkol Kaewbumrung¹  Benchawan Wiwatanapataphee²  Somsak Orankitjaroen¹  Thanongchai Siriapisith³ 

[1] Department of Mathematics, Faculty of Science, Mahidol University Bangkok 10400;Department of Mathematics and Statistics, Curtin University of Technology;Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University

关键词: Mathematical model;    Numerical simulation;    Finite element method;    Cardiovascular disease;    Coronary arteries;   

DOI  :  10.4172/2155-6180.1000344

来源: Hilaris Publisher

【 摘 要 】

In this paper, we propose a mathematical model of turbulence flow of fluid through a deformable channel to study the pulsatile blood flow in the coronary system with arterial stenosis. Blood is assumed to be an incompressible non- Newtonian fluid and its motion is considered as turbulent and modelled by the mass and momentum conservations with turbulent mixing energy and specific dissipation rate. The mechanical deformation of the arterial wall is modelled by a hyperelastic differential equation. The pulsatile behaviour during each heartbeat is assigned on the entrance and exit boundaries. Numerical simulation based on the Finite Element method for the solution of arterial wall deformation, and the Arbitrary Lagrangian Eulerian Finite Volume method for the turbulence fluid-flow solution is used to investigate the effect of stenosis severity at the proximal part of the left anterior descending artery on the blood velocity, the pressure distribution and the wall shear stresses along the flow direction.

【 授权许可】

Unknown