Protocol: Leveraging a demographic and health surveillance system for Covid-19 Surveillance in rural KwaZulu-Natal

Wellcome Open Research

article

Anne Derache¹  Theresa Smit¹  Thandeka Khoza¹  Resign Gunda¹  Thobeka Mngomezulu¹  Dickman Gareta¹  Nomathamsanqa Majozi¹  Eugene Ehlers¹  Jaco Dreyer¹  Siyabonga Nxumalo¹  Njabulo Dayi¹  Gregory Ording-Jesperson¹  Nothando Ngwenya¹  Emily Wong¹  Collins Iwuji¹  Maryam Shahmanesh¹  Janet Seeley¹  Tulio De Oliveira⁷  Thumbi Ndung'u¹  Willem Hanekom¹  Kobus Herbst¹  Mark J. Siedner¹  Guy Harling¹ 

[1] Africa Health Research Institute;Massachusetts General Hospital;Harvard Medical School;Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex;Institute for Global Health, University College London;Global Health and Development Department, London School of Hygiene & Tropical Medicine;KwaZulu-Natal Research Innovation and Sequencing Platform ,(KRISP)), School of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal;Department of Global Health, University of Washington;Division of Infection and Immunity, University College London;HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu Natal;Max Planck Institute for Infection Biology;SAPRIN, South African Medical Research Council;MRC/Wits Rural Public Health & Health Transitions Research Unit ,(Agincourt), University of the Witwatersrand;Department of Epidemiology and Harvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health

关键词: Covid-19;    Surveillance;    South Africa;    Screening;    Health and Demographic Surveillance System;   

DOI  :  10.12688/wellcomeopenres.15949.2

学科分类：内科医学

来源: Wellcome

【 摘 要 】

A coordinated system of disease surveillance will be critical to effectively control the coronavirus disease 2019 (Covid-19) pandemic. Such systems enable rapid detection and mapping of epidemics and inform allocation of scarce prevention and intervention resources. Although many lower- and middle-income settings lack infrastructure for optimal disease surveillance, health and demographic surveillance systems (HDSS) provide a unique opportunity for epidemic monitoring. This protocol describes a surveillance program at the Africa Health Research Institute’s Population Intervention Platform site in northern KwaZulu-Natal. The program leverages a longstanding HDSS in a rural, resource-limited setting with very high prevalence of HIV and tuberculosis to perform Covid-19 surveillance. Our primary aims include: describing the epidemiology of the Covid-19 epidemic in rural KwaZulu-Natal; determining the impact of the Covid-19 outbreak and non-pharmaceutical control interventions (NPI) on behaviour and wellbeing; determining the impact of HIV and tuberculosis on Covid-19 susceptibility; and using collected data to support the local public-sector health response. The program involves telephone-based interviews with over 20,000 households every four months, plus a sub-study calling 750 households every two weeks. Each call asks a household representative how the epidemic and NPI are affecting the household and conducts a Covid-19 risk screen for all resident members. Any individuals screening positive are invited to a clinical screen, potential test and referral to necessary care – conducted in-person near their home following careful risk minimization procedures. In this protocol we report the details of our cohort design, questionnaires, data and reporting structures, and standard operating procedures in hopes that our project can inform similar efforts elsewhere.

【 授权许可】

CC BY