Feasibility of Hydroethanolic Solvent System for Bioactive Compounds Recovery from Aerial Parts of Silybum marianum and Kinetics Modeling

Journal of Human, Environment, and Health Promotion

article

Fatemeh Mojarradi¹  Mandana Bimakr¹  Ali Ganjloo¹ 

[1] Department of Food Science and Engineering, Faculty of Agriculture, University of Zanjan

关键词: Hydroethanolic solvent system;    Silybin;    Silybummarianum;    Spectrophotometric analysis;    Scanning electron microscope;   

DOI  :  10.52547/jhehp.7.3.129

来源: Journal of Human Environment and Health Promotion

【 摘 要 】

Background: Silybum marianum is considered as one of the valuable medicinal plants. This study focused on maximum recovery of total extractable compounds (TEC), anti-radical capacity (AC), and silybin content as a major phenolic compound using hydroethanolic solvent system (HSS). Methods: The HSS consisted of different ratios of ethanol (EtOH) and water (H2O). The AC was determined using spectrophotometric analysis. High-performance liquid chromatography was used for analyzing the silybin content. The cells morphology and the mass transfer kinetics were investigated using scanning electron microscope and Peleg model respectively. Results: Based on the results, the highest TEC (154.60 ± 2.4 mg/g), AC (39.19 ± 0.30 of % DPPHsc and 28.15 ± 0.51 of % OHsc), and silybin (4400 ± 33.00 mg/ kg) were obtained using HSS (80%v/v of EtOH). Moreover, high correlation was found between AC and silybin content. Mass transfer kinetics was successfully explained using Peleg model (R2 = 0.9970, RMSE = 2.274, and E = 1.22%). Further, intense cellular disruption during HSS caused accelerated release of bioactive compounds. Conclusion: The HSS composed of 80% v/v of EtOH was found as an efficient system for successful recovery of bioactives which could be introduced as a natural ingredient for food and pharmaceuticals industries.

【 授权许可】

Unknown