Port-site Metastasis from Gall Bladder Adenocarcinoma with Squamous Differentiation Following Laparoscopic Cholecystectomy: A Rare Case Report

Asian Pacific Journal of Cancer Care

article

Kafil Akhtar¹  Asfa Shams²  Sadaf Abbas¹  Suhailur Rehman¹ 

[1] Department of Pathology;Department of Pathology, JNMC, AMU

关键词: Adenocarcinoma;    Gallbladder;    Immunohistochemistry;    Metastases;    Port site.;   

DOI  :  10.31557/apjcc.2023.8.2.441-443

学科分类：内科医学

来源: West Asia Organization for Cancer Prevention

【 摘 要 】

Port site cutaneous metastasis of gallbladder cancer is an exceedingly infrequent phenomenon with very few cases reported in the past. Herein, we report a case of port site cutaneous metastases of gallbladder adenocarcinoma in a 57 years old female. Physical examination revealed a non healing ulcer in the epigastric region. FNA was suggestive of poorly differentiated carcinoma. Biopsy demonstrated atypical cells. Immunohistochemical analysis showed diffuse cytoplasmic staining with CK 7 and p63 showed focal nuclear positivity in tumour cells. This confirmed the diagnosis of metastastatic gall bladder adenocarcinoma with squamous differentiation. Diagnosis in such a case can be very challenging as the differential of primary cutaneous malignancies should also be kept in mind.

【 授权许可】

CC BY