The Immunomodulatory Properties of Vitamin D

Mediterranean Journal of Rheumatology

article

Lambros Athanassiou¹  Clio P. Mavragani¹  Michael Koutsilieris¹ 

[1] Department of Physiology, Medical School, University of Athens

关键词: vitamin D;    immunomodulation;    innate immunity;    adaptive immunity;    immune tolerance;    vitamin D deficiency;   

DOI  :  10.31138/mjr.33.1.7

学科分类：社会科学、人文和艺术（综合）

来源: PCO Convin S.A.

【 摘 要 】

Since its discovery, vitamin D was shown to have both immunostimulatory and immunomodulatory effects on the immune system. A growing body of evidence so far linked vitamin D deficiency with the development and severity of several systemic and organ specific autoimmune/inflammatory diseases, such as systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis. In the present report, the multiple and diverse effects of vitamin D on the immune system are reviewed.

【 授权许可】

CC BY-NC