Comparing the Diagnostic Value of Four Dementia Tests in the Amnestic and Healthy Elderly

Basic and Clinical Neuroscience

article

Fatemah Khamseh¹  Gholamreza Hadjati¹  Hossein Nahvinejad²  Zahra Nouparast¹  Masomeh Salehi¹  Maryam Noroozian³  Mahshid Foroughan⁴  Farshid Alaedini⁵  Afrooz Saffarifard²  Faraneh Farin¹  Mehrdad Khansari¹  Maryam Pourseid Mohammad²  Zahra Ahmadi² 

[1] Iranian Association of Alzheimer’s Disease;Iranian State Welfare Organization;Department of Neurology, Tehran University of Medical Sciences;Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences;Shafa Health Research Center

关键词: Alzheimer’s disease;    Diagnosis;    Mini-mental state examination;    Abbreviated mental test score;    Functional assessment staging tool;   

DOI  :  10.32598/bcn.2022.1745.1

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: This study aimed to compare the diagnostic value of four questionnaires for the diagnosis of neurocognitive disorders (NCDs) in the elderly. Methods:  In this project, people older than 60 years who lived in Tehran were investigated. A total of 99 literate cases were enrolled in the study, and four questionnaires, including functional assessment staging tool (FAST), abbreviated mental test score (AMTS), mini-mental state examination (MMSE), and modified Persian test of elderly for assessment of cognition and executive function (PEACE) were completed for them. They were then referred to a neuropsychiatrist, and the status of their cognition and neurobehavior was determined. The specialists were blinded to the results of the tests. Results: Of the 99 participants studied, 39 cases were healthy, eight cases had mild Alzheimer’s disease, 38 had amnesic MCI, five cases had secondary dementia, and nine cases had mixed vascular dementia and Alzheimer’s disease. The area under the ROC curve for distinguishing the healthy group from the rest of the population was 0.692, 0.629, 0.734, and 0.751 for the FAST, AMTS, MMSE, and NBCSS questionnaires, respectively. Conclusion: MMSE and NBCSS tests had better diagnostic power than the other two tests to distinguish the healthy group from the rest of the population.

【 授权许可】

Unknown