Brain Structural Correlates of Intelligence in Attention Deficit Hyperactivity Disorder (ADHD) Individuals

Basic and Clinical Neuroscience

article

Farnaz Faridi¹  Ashkan Alvand¹  Reza Khosrowabadi¹ 

[1] Institute for Cognitive and Brain Sciences, Shahid Beheshti University

关键词: Attention deficit hyperactivity disorder (ADHD);    Magnetic Resonance Imaging;    Intelligence;    Grey matter density;   

DOI  :  10.32598/bcn.2021.2244.1

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: Neuroimaging evidence has shown the relationship of intelligence with several structural brain properties in normal individuals. However, this relationship with attention deficit hyperactivity disorder (ADHD) needs to be investigated. Methods: We estimated grey matter (GM) density of the brain using magnetic resonance imaging (MRI) scan on 56 ADHD individuals, including 30 combined individuals (Mean±SD age: 10.44±2.41, intelligence quotient: [IQ]=112.13±13.15, male, 24 right hands) and 26 inattentive individuals (mean age =11.39±2.1, IQ=107.44±13.98, male, 28 right hands) as well as 30 IQ matched healthy control group (mean age=11.08±2.15, IQ=115±13.56, male, 23 right hands). Results: In this study, two statistical approaches were used. In the first approach, region-based as well as the whole association patterns between full-scale IQ and GM were computed and compared between groups. The second approach was to examine the differential pattern of GM density without considering IQ in three groups. Conclusion: Results showed significant differences between the ADHD group and the control. This finding could indicate that intelligence is not purely based on the density of GM in certain brain regions; it is a dynamic phenomenon and drastically changes neurodevelopmental disorders.

【 授权许可】

Unknown