Evaluation of Date Extract on Nerve Conduction Velocity in Male Rats

Basic and Clinical Neuroscience

article

Hossein Ali Ebrahimi¹  Mandana Jafari²  Narges Khanjani¹  Najmeh Moradi³ 

[1] Neurology Research Center, Kerman University of Medical Sciences;Pharmaceutics Research Institute of Neuropharmacology, Kerman University Medical Sciences;Afzalipour Medical Faculty Kerman, University of Medical Sciences

关键词: Date extract;    Nerve conduction velocity;    Male rats;    Sciatic nerve;   

DOI  :  10.32598/bcn.2021.878.2

来源: Iran University of Medical Sciences

【 摘 要 】

Introduction: Neuropathy is a condition in which the Peripheral Nervous System (PNS) is disordered. Studying the effects of antioxidants on the performance improvement of this system is vital. This study aimed to investigate the effects of date extract on Nerve Conduction Velocity (NCV), Distal Motor Latency (DML), and wave height of the sciatic nerve in male rats. Methods: This laboratory study used 24 male Wistar rats weighing 250-300 g, divided into the test and control groups. The test group received 10% date extract daily, at 4 mL /kg of body weight, for three weeks. In the beginning, nerve Conduction Velocity (NCV), Distal Motor Latency (DML), and wave height of the sciatic nerve were examined in all animals and re-examined for NCV three weeks later. P-values lower than 0.05 were considered significant.  Results: Sciatic NCV and wave height were significantly increased; however, compared to the control group, DML of the knee significantly declined in the test group. Conclusion: The compositions of date extract accelerate electrical signal transmission.

【 授权许可】

Unknown