What outcomes have been reported on patients following open lower limb fracture, and how have they been measured?

Bone & Joint Research

article

Alexander L. Aquilina¹  Henry Claireaux¹  Christian O. Aquilina²  Elizabeth Tutton¹  Raymond Fitzpatrick³  Matthew L. Costa¹  Xavier L. Griffin⁴ 

[1] Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford;Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, Southmead Hospital;Nuffield Department of Population Health, University of Oxford;Bone and Joint Health, Blizard Institute, Queen Mary University of London

关键词: Open fracture;    Open lower limb fracture;    Core outcome set;    Outcome;    Outcome measurement instrument;    Open lower limb fractures;    bone union;    orthopaedic trauma;    clinician;    clinical studies;    morbidity;    lower limb fracture;    patient-reported outcome measures (PROMs);    randomized controlled trial;    open fracture;   

DOI  :  10.1302/2046-3758.122.BJR-2022-0116.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

AimsOpen lower limb fracture is a life-changing injury affecting 11.5 per 100,000 adults each year, and causes significant morbidity and resource demand on trauma infrastructures. This study aims to identify what, and how, outcomes have been reported for people following open lower limb fracture over ten years.MethodsSystematic literature searches identified all clinical studies reporting outcomes for adults following open lower limb fracture between January 2009 and July 2019. All outcomes and outcome measurement instruments were extracted verbatim. An iterative process was used to group outcome terms under standardized outcome headings categorized using an outcome taxonomy.ResultsA total of 532 eligible studies were identified, reporting 1,803 outcomes with 786 unique outcome terms, which collapsed to 82 standardized outcome headings. Overall 479 individual outcome measurement instruments were identified, including 298 outcome definitions, 27 patient- and 18 clinician-reported outcome measures, and six physical performance measures. The most-reported outcome was ‘bone union/healing’ reported in over 50% of included studies, while health-related quality of life was only measured in 6% of included studies.ConclusionOutcomes reported for people recovering from open lower limb fracture are heterogeneous, liable to outcome reporting bias, and vary widely in the definitions and the measurement tools used to collect them. Outcomes likely to be important to patients, such as quality of life and measures of physical functioning, have been neglected. This systematic review identifies the need to unify outcome measures reported on patients recovering from open lower limb fracture; this may be addressed by creating a core outcome set.

【 授权许可】

CC BY-NC