Osteoporosis: current screening methods, novel techniques, and preoperative assessment of bone mineral density

Bone & Joint Research

article

Khalid Al-Hourani¹  Shao-Ting Jerry Tsang¹  A. Hamish R. W. Simpson¹ 

[1] Department of Trauma and Orthopaedics, Royal Infirmary of Edinburgh

关键词: Osteoporosis;    Fragility fracture;    Imaging;    bone mineral density (BMD);    Cortical bone;    plain radiographs;    hip fractures;    distal radius;    Bone quality;    osteoporotic fractures;    fragility fractures;    forearms;   

DOI  :  10.1302/2046-3758.1012.BJR-2021-0452.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

Osteoporosis is “a disease characterisedby low bone mass and micro-architecturaldeterioration of bone tissue, leading toenhanced bone fragility and a consequentincrease in fracture risk”.1 While it is knownto be a multifactorial metabolic disease ofthe bone,1 the exact pathoaetiology remainsunclear.2 One recent development is the'gut-bone axis' theory which proposes acritical role of the gut microbiome and itsmetabolites in the development of osteoporosis.2,3 It is defined radiologically as a dualenergy X-ray absorptiometry (DXA) score >2.5 standard deviations below the youngadult mean.1 It is estimated that there are2.7million fragility fracture presentationsannually within the European Union, culminating in €37.5 billion in healthcare costs.

【 授权许可】

CC BY-NC