Do E-cigarettes and vaping have a lower risk of osteoporosis, nonunion, and infection than tobacco smoking?

Bone & Joint Research

article

Thomas Nicholson¹  Aaron Scott²  Matthew Newton Ede³  Simon W. Jones¹ 

[1] MRC-ARUK Centre for Musculoskeletal Ageing Research, Medical School, Queen Elizabeth Hospital, University of Birmingham;Birmingham Acute Care Research Group Institute of Inflammation and Ageing ,(IIA), University of Birmingham;Royal Orthopaedic Hospital

关键词: Vaping;    E-Cigarette;    Osteoblast;    Bone;   

DOI  :  10.1302/2046-3758.103.BJR-2020-0327.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

Cigarette smoking is significantly associatedwith reduced bone mineral density (BMD),increased risk of fracture, and reducedfracture healing.1,2 Smoking is also independently associated with increased incidence of post-surgery complications suchas infection and aseptic loosening followingarthroplasty.3-6 While cigarette consumptionhas declined over the past decade, the use ofelectronic cigarettes (E-cigarettes), or vaping,has risen dramatically, partly due to beingregarded as a safer alternative to smoking.7-9Indeed, Public Health England guidancesuggests that E-cigarettes are 95% saferthan cigarettes, fuelling public perception ofnegligible risk.8 Increased use of E-cigaretteswill undoubtedly represent a harm reduction in comparison to cigarettes due to lessexposure to carcinogens and toxicants.2,10However, E-cigarette usage still results insystemic exposure to numerous and potentially harmful vapour constituents, includingnicotine (in nicotine-containing liquids),flavouring chemicals, and reactive aldehydes, particularly for highly vascularizedtissues such as the bone.

【 授权许可】

CC BY-NC