Identifying early decline of daily function and its association with physical function in chronic kidney disease: performance-based and self-reported measures

PeerJ

article

Hui-Mei Chen¹  Shih-Ming Hsiao³  Mei-Chuan Kuo⁴  Yi-Ching Lo⁶  Mei-Feng Huang²  Yi-Chun Yeh²  Cheng-Fang Yen⁸  Cheng-Sheng Chen⁸ 

[1] Department of Occupational Therapy, College of Health Science, Kaohsiung Medical University;Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University;Department of Nursing, Kaohsiung Medical University Hospital;Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital;Faculty of Renal Care, College of Medicine, Kaohsiung Medical University;Department of Pharmacology, College of Medicine, Kaohsiung Medical University;Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University;Department of Psychiatry, Kaohsiung Medical University Hospital;Department of Psychiatry, College of Medicine, Kaohsiung Medical University

关键词: Chronic kidney disease;    Activities of daily living;    Endurance;    Muscle strength;   

DOI  :  10.7717/peerj.5286

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Objective To verify self-reported basic and instrumental activities of daily living (IADL) with a disability and the results of performance-based tests (namely the Taiwan performance-based IADL (TPIADL), the 2-minute step test (2MST), the 30-second chair-stand test (30-s CST), and handgrip dynamometer measurement) to identify disability early and assess the associations with functional fitness in patients with advanced chronic kidney disease (CKD). Methods A cross-sectional study of 99 patients with stage 4–5 CKD and 57 healthy elderly adults were recruited. Self-reported measures were used to collect information on basic (Barthel Index) and IADL (Lawton–Brody scale). Objective measures of the TPIADL and functional fitness (2MST, 30-s CST, handgrip dynamometer) were also assessed. Results Only IADL, as detected by the TPIADL, were impaired to a greater extent in the CKD patients than those of healthy elderly adults. Among all the patients with CKD, a greater impairment in the TPIADL remained statistically associated with a lower ability in the 2MST. A one step increase in the 2MST score was significantly associated with an improvement of 0.2 s in the total performance time of the TPIADL. Conclusion Performance-based measures, such as the TPIADL, may detect a functional limitation before it becomes measurable by traditional self-reported basic and IADL scales; functional limitation is mainly associated with cardiac endurance for advanced CKD.

【 授权许可】

CC BY