Analyzing clinical characteristics of patients with different cumulative hemodialysis durations: a cross-sectional study

PeerJ

article

Xu Chen¹  Li Yuan¹  Yuan Zhang¹  Houyong Dai¹  Yaping Fan¹  Xiaolan Chen¹ 

[1] Department of Nephrology, Affiliated Hospital of Nantong University

关键词: Clinical characteristics;    Hemodialysis;    Kidney failure;    Anemia;    Serum albumin;    Age of onset;   

DOI  :  10.7717/peerj.10852

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

BackgroundThe objective of this study was to examine the clinical characteristics of patients with different cumulative hemodialysis (HD) durations, so as to improve their survival rate.MethodsIn this cross-sectional study, we extracted background information and relevant clinical data from 145 patients who were undergoing maintenance HD three times a week at the Affiliated Hospital of Nantong University between January 1998 and January 2019. The study subjects were divided into four groups according to the duration of their HD: 15 years of HD. We collected the medical history and relevant clinical parameters for each subject, and measured the urea reduction ratio (URR), hemoglobin (Hb), serum calcium, phosphorus, parathyroid hormone (iPTH), and serum albumin (ALB) levels for each group.Results15 years groups was significantly lower than in the <5 years and 5–10 years groups (P = 0.002, P < 0.001, P = 0.012, and P = 0.0025, respectively). The most common cause of end-stage renal disease (ESRD) was chronic glomerulonephritis. We found no significant differences in URR, Hb, serum calcium, serum phosphorus, iPTH, and ALB levels.ConclusionA prolonged HD duration was related to a younger mean age at the start of HD treatment. The leading cause of ESRD was chronic glomerulonephritis. We predominantly found diabetic nephropathy in the group with a duration of <5 years cumulative HD. Most of the indexes related to hemodialysis almost satisfied the recommended values in these patients.

【 授权许可】

CC BY