Influence of Pretransplant Anemia on Red Blood Cell Transfusions in Myeloma Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

Global Journal of Transfusion Medicine

article

Augustine, Merline¹  Murugesan, Mohandoss²  Nair, Chandran K.³  Nayanar, Sangeetha Keloth¹ 

[1] Department of Transfusion Medicine, Goa Medical College;Department of Transfusion Medicine, Malabar Cancer Centre;Department of Clinical Hematology and Medical Oncology, Malabar Cancer Centre

关键词: DBS-0;    Oman;    RHD gene;   

DOI  :  10.4103/gjtm.gjtm_13_22

学科分类：社会科学、人文和艺术（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

RHD variants are divided into three categories; weak D, partial D, and Del. The variants detection is important during donor testing and pregnancy. Studies shown that the detection of D variants may be missed by standard serologic methods including Indirect Antihuman Globulin Test and may cause anti-D immunization when exposed to D-negative individual. The limitations of serology can be overcome by RHD gene molecular typing. We describe for the first time a possible novel DBS-0 like allele partial D which revealed serological D and E negative in an Omani donor that is different from the previously described DBS-0 with serological positive D and partial E.

【 授权许可】

CC BY-NC-SA