Antimicrobial potential of extract fractions of ficus vogelii Miq.

Environmental Disease

article

Stephen, Akataobi Uche¹ 

[1] Department of Biochemistry, Faculty of Basic Medical Sciences, University of Calabar, Calabar

关键词: Candida albicans;    Escherichia coli;    Ficus vogelii Miq.;    Salmonella typhimurium;    Streptococcus aureus;   

DOI  :  10.4103/ed.ed_7_20

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Purpose:  Microorganisms are responsible for a host of infectious disease diagnosed in human. Studies have shown that extracts of medicinal plants contain antimicrobial properties effective in the treatment of these infectious diseases. This study evaluated the antimicrobial potency of ficusvogeliiMiq. extract fractions on selected microorganisms. Material and Method:  The leave extract of the plant was prepared with n-hexane, crude, and methanol, serially diluted, and screened against Escherichiacoli,Staphylococcusaureus,Salmonellatyphimurium, and Candidaalbicans for zones of inhibition, minimum inhibitory concentration, resistance, and sensitivity test at a concentration of 12.5, 25, 50, and 100 mg/ml. Result:  Crude and n-Hexane extract fractions inhibited E.coli and S. typhimurium effectively at different concentrations. Methanol fraction less inhibited E. coli only while all the extract fractions did not show any antimicrobial potency against S. aureus and Candida abicans. Conclusion:  This study concludes that crude and n-hexane extract of ficusvogelii is a potent antimicrobial agent against E. coli andS.typhimurium at a concentration of as low as 12.5 μg/ml.

【 授权许可】

CC BY-NC-SA