RNA Oligomerisation without Added Catalyst from 2′,3′-Cyclic Nucleotides by Drying at Air-Water Interfaces

ChemSystemsChem

article

Dr. Avinash Vicholous Dass¹  Sreekar Wunnava¹  Juliette Langlais¹  Beatriz von der Esch²  Maik Krusche¹  Lennard Ufer¹  Nico Chrisam¹  Romeo C. A. Dubini³  Dr. Florian Gartner⁴  Severin Angerpointner⁴  Christina F. Dirscherl¹  Dr. Petra Rovó³  Dr. Christof B. Mast¹  Dr. Judit E. Šponer⁶  Christian Ochsenfeld²  Erwin Frey⁴  Dieter Braun¹ 

[1] Faculty of Physics, Systems Biophysics, Ludwig-Maximilians-Universität München;Chair of Theoretical Chemistry, Department of Chemistry, Ludwig-Maximilians-Universität München;Faculty of Chemistry and Pharmacy, Ludwig-Maximilians-Universität München;Faculty of Physics, Statistical and biological physics, Ludwig-Maximilians-Universität München;Institute of Science and Technology Austria c/o NMR Facility, Am Campus 1;Institute of Biophysics Academy of Sciences of the Czech Republic;Max Planck Institute for Solid State Research

关键词: RNA;    Polymerisation;    Prebiotic chemistry;    Non-equilibrium;    Air-water interfaces;   

DOI  :  10.1002/syst.202200026

来源: Wiley

【 摘 要 】

Without catalyst! A non-enzymatic, spontaneous route to the formation of short, mixed-sequence RNA strands from 2′,3′-cyclic ribonucleotides is shown. The reaction occurs by drying at the air–water interfaces.

【 授权许可】

Unknown