Tuning the Kinetic Trapping in Chemically Fueled Self-Assembly

ChemSystemsChem

article

Brigitte A. K. Kriebisch¹  Christine M. E. Kriebisch¹  Alexander M. Bergmann¹  Dr. Caren Wanzke¹  Dr. Marta Tena-Solsona¹  Job Boekhoven¹ 

[1] School of Natural Science, Department of Chemistry, Technische Universität München

关键词: Dynamic instability;    Dynamic fibers;    Kinetically trapping;    Microenvironmental change;    pKa shift;   

DOI  :  10.1002/syst.202200035

来源: Wiley

【 摘 要 】

Dynamic molecular self-assemblies like microtubules show dynamic instabilities. Synthetic analogs of such dynamic assemblies regulated by chemical-fueled reaction cycles often face the challenge to display dynamic instability. In this work, we show how molecular design can be used to tune the degree of kinetically trapping to approach dynamic instability.

【 授权许可】

Unknown