From Sequence Analysis to Application: Role of Bioinformatics to Understand Biological Systems

Resonance

article

Jaspreet Kaur¹ 

[1] Assistant Professor Zoology Department of Maitreyi College University of Delhi

关键词: In-silico;    ‘omic’ studies;    next-generation sequencing;    bioinformatic literacy.;   

DOI  :  10.1007/s12045-022-1506-z

学科分类：社会科学、人文和艺术（综合）

来源: Springer

【 摘 要 】

The field of biological sciences enumerates various importantaspects of life forms, some of which remain mysterious to explainor validate. Though there has been a revolutionary advancementof tools and techniques to study different biologicalphenomena under laboratory conditions, there are significantlimitations with implementing each concept in the laboratory.Sometimes, it is practically impossible to simulatethe actual environmental conditions of living systems underin-vitro settings, or sometimes the requirements of life arediscordant with various analytical techniques, or the studyof complex evolutionary processes becomes technically difficultusing wet-lab methods. Thus, these experimental challengesconfine our boundary to explore the real world of biologicalsystems, which may lead to the acquisition of knowledgewith few lacunae. Bioinformatics as a discipline triesto fill those spaces to a major extent using in silico analysisand provides a deeper theoretical foundation and validationof existing biological principles. The importance and potentialof bioinformatics have been witnessed in the pandemictimes to fight against Covid-19. From developing new drugsand vaccines to crop improvement and space and environmentstudies, the field of bioinformatics has many prospects.This article aims to provide a bird’s-eye view of different applicationsand cutting-edge bioinformatics approaches to understandbiological systems and the emerging need to integratethis course into the education framework.

【 授权许可】

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