Myocardial Ischemia Detection by a Sensitive PumpProbe Atomic Magnetometer

Journal of Lasers in Medical Sciences

article

AminZamani¹  MalihehRanjbaran²  Mohammad Mehdi Tehranchi¹  Seyedeh MehriHamidi¹  Seyed Mohammad HoseinKhalkhali³ 

[1] Laser and Plasma Research Institute, Shahid Beheshti University;Department of Physics, Central Tehran Branch, Islamic Azad University;Physics Department, Kharazmi University

关键词: Magnetocardiography (MCG);    Myocardial ischemia;    Optical atomic magnetometer;    MCG trace;    Hanle effect;   

DOI  :  10.34172/jlms.2022.24

学科分类：基础医学

来源: Shahid Beheshti University of Medical Sciences

【 摘 要 】

Introduction: Magnetocardiography (MCG) based on optical atomic magnetometers has shown promise for detecting heart diseases accurately. Different methods were introduced to improve the sensitivity of detecting magnetic fields during cardiac activity.Methods: In this paper, an optical pump-probe magnetometer operated on the ground-state Hanle effect based on the zero-field level crossing technique was developed and the laser output signal was optimized in an unshielded environment. Then, the optical magnetometer was utilized to record the simulated MCG trace of different stages of myocardial ischemia.Results: The probe output light intensity followed the variation of cardiac magnetic field (MCG trace) generated by the Helmholtz coil accurately.Conclusion: Based on the results, the feasibility of our highly sensitive optical magnetometer in tracing showed no change in the P-QRS-T waveform associated with ischemic heart disease (IHD), where P indicates atrial depolarization, QRS is responsible for ventricular depolarization, and T represents ventricular repolarization.

【 授权许可】

CC BY