Physiology Of Calcitriol, Its Role In Body Functions And Highlights About Immunological And Thyroid Activities: A Molecular View On Vitamin D Receptors And Gene Polymorphism.

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Pundalik Rama Naik¹  Ravichandra V²  Swapnali³  Prathibha KN³  Divija DA³  Suchetha Kumari.⁴ 

[1] Department of Biochemistry Kodagu institute of Medical Sciences, Madikeri, and PhD Scholler at KS Hegde Medical College;Dept of Pharmacology KSEMA;Department of Biochemistry Kodagu institute of Medical Sciences;Dept of Biochemistry

关键词: Vitamin D;    steroid hormone;    gene polymorphism.;   

DOI  :  10.33887/rjpbcs/2023.14.3.10

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

Vitamin D is a secosteroid hormone, which is attracting the attention of the scientists for itstherapeutic functions. As it is playing the pleotropic role in multiple physiological process, the deficiencyof vitamin D is considered as the major health issue. The main reason for the deficiency of vitamin D is lackof exposure to the sunlight. The vitamin D receptor is a member of steroid hormone super family. Recentlythe highlighting issues are the action of vitamin D in non-skeletal tissues, cardiovascular, diabetes mellitus,cancer. currently, there is a need to increase the vitamin D status in individuals worldwide as it has beenshown to improve the auto immune and infectious disease, type-2 diabetes mellitus, neurocognitivedisorders. This review is elucidating the central role of vitamin D in maintaining the overall health.Highlights about vitamin D receptors and a molecular view on vitamin D receptor gene polymorphism.

【 授权许可】

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