Assessment Of Iron Status In End Stage Renal Disease Patients On Hemodialysis.

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Vijayabanu N¹  Sangeetha P¹  Sudha R²  Anandhi S.³ 

[1] Govt Mohan Kumaramangalam Medical college;Biochemistry, Vinayaga Mission Kirupanandha variyar Medical college;Biochemistry, Govt Mohan Kumaramangalam Medical college

关键词: Chronic Kidney Disease;    End Stage Renal Disease;    Hemodialysis;    Serum Ferritin;    Serum Iron;    Total iron binding capacity.;   

DOI  :  10.33887/rjpbcs/2021.12.1.22

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

Chronic kidney disease is a pathological condition that results from a gradual, permanent loss of kidneyfunction. Anemia is a common comorbidity of End Stage Renal Disease patients who are on maintenance hemo- dialysis. This study aims to find out the iron status in maintenance hemodialysis patients. Serum iron, Ferritinand Transferrin saturation are widely used together to assess iron status. A total of 80 End Stage Renal Diseasepatients of age 18-80yrs on Hemodialysis were included. Serum iron,Total iron binding capacity(TIBC) and SerumFerritin were measured . We found that, the mean level of serum ferritin was 365.91±198.3 μg/l . Although theserum ferritin levels were within the normal range, hemoglobin and serum iron levels were lower which indicatespoor iron status. Also serum iron levels had a significant negative correlation with Ferritin (p-value 0.04) . Thisindicates, high ferritin in hemodialysis is due to non iron related factors such as inflammation. Periodic assess- ment of iron status is necessary while managing anemia in hemodialysis patients and this probably will help inreducing morbidity and mortality.

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