Impact of Escherichia coli toxins on blood chemistry and intestine of Oreochromis niloticus

Research Journal of Pharmaceutical, Biological and Chemical Sciences

article

Amal M. Yacoub¹  Sherifa Mostafa M. Sabra¹  Mona Khaled D. Al-Kourashi.¹ 

[1] Biology Dept., Science College, Taif University;Pollution Lab. / National Institute of Oceanography and Fisheries.;Department of Microbiology / Animal Health Research Institute

关键词: experimental study;    Oreochromis niloticus;    Escherichia coli;    blood chemistry;    intestine.;   

DOI  :  10.33887/rjpbcs/2019.10.4.14

学科分类：工程和技术（综合）

来源: Research Journal of Pharmaceutical, Biological and Chemical Sciences

【 摘 要 】

Fish of Oreochromis niloticus (Linnaeus, 1758) were infected with different concentrations of3 5 6 7 9 10 Enterotoxigenic Escherichia coli (ETEC) as (10 -10 , 10 -10 and 10 -10 CFU /ml water). The study hadconducted to detect experimentally the impact of E. coli toxins on O. niloticus fish throughout the bloodchemistry and histopathological changes of intestine. The values of glucose, cholesterol and triglyceridesranged between (346.42 mg/dl- 1.09 mg/dl), (279.45 mg/dl- 87.32 mg/dl) and (413.39 mg/dl- 78.84 mg/dl)respectively. The intestine of O. niloticus infected with E. coli showed degeneration of mucosa and submucosa,necrosis of villi, hyperplasia of goblet cells, infiltration of WBCs, hemorrhage, fragmentation and necrosis ofmuscular layer beside degeneration of serosa. The present investigation revealed that exposure of O. niloticusto E. coli caused disorders in metabolism and induced pathological changes in intestine which impedeabsorption of food stuff and finally caused mortality in the highest concentrations. It is recommended toprevent fishing in seas or rivers polluted with sewage or usage of sanitation in farms.

【 授权许可】

All Rights reserved