期刊论文详细信息
Journal of Thoracic Disease
Peri-operative outcomes of bariatric surgery in obstructive sleep apnoea: a single-centre cohort study
article
Cristiano van Zeller1  Richard Brown1  Michael Cheng1  Johan Meurling1  Barbara McGowan2  Joerg Steier1 
[1] Lane Fox Respiratory Unit/Sleep Disorders Centre, Guy’s and St Thomas’ NHS Foundation Trust;Department of Endocrinology and Diabetes, Guy’s and St Thomas’ NHS Foundation Trust;King’s College London, Faculty of Life Sciences and Medicine
关键词: Obesity;    obstructive sleep apnoea (OSA);    bariatric surgery;    postoperative complications;    continuous positive airway pressure (CPAP);   
DOI  :  10.21037/jtd-22-1501
学科分类:呼吸医学
来源: Pioneer Bioscience Publishing Company
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【 摘 要 】

Background: The prevalence of obstructive sleep apnoea (OSA) is increasing worldwide. Bariatric surgery is an option where conventional measures to achieve weight loss fail. We compared peri-operative outcomes in patients living with obesity with and without OSA undergoing bariatric surgery. Methods: Retrospective cohort study of consecutive patients undergoing bariatric surgery at a tertiary referral centre. Data were extracted from electronic patient records. Primary outcomes were the rate of peri-operative complications and level of respiratory support. Secondary outcomes were length of stay (LOS), and the highest level of care required. Results: A total of 302 patients underwent surgery [age 47 (±11.6) years, 238 (78.8%) female, body mass index (BMI) 48.1 (±7.8) kg/m2]. A total of 101 (33.4%) patients had moderate or severe OSA, or mild OSA with significant sleepiness, and were prescribed continuous positive airway pressure (CPAP), whilst 201 (66.6%) had mild OSA without symptoms or no OSA and weren’t. Patients requiring CPAP were more obese (BMI 50.2 vs. 47.0 kg/m2, P=0.002). Complications were analysed individually and according to the Clavien-Dindo classification. The incidence of each individual complication did not differ between groups. When grouped into Clavien-Dindo grades, only grade I complications differed: CPAP 9% vs. non-CPAP 2.6%, P=0.02). LOS was longer in the CPAP group [3 (1.5) vs. 2 (1.0) days, P=0.002]. Conclusions: The rate of peri-operative complications in patients with OSA undergoing bariatric surgery is low and can be addressed by the provision of CPAP therapy in most cases. However, a longer LOS and more frequent Grade I complications requires selection of appropriate post-operative monitoring.

【 授权许可】

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