Prevalence of Common Human Coronaviruses (NL63, 229E, and OC43) in Adults before the COVID-19 Pandemic: a Single-Center Study from Turkey, 2015–2020

Japanese journal of infectious diseases

article

Meliha Cagla Sonmezer¹  Taha Koray Sahin²  Enes Erul²  Gulcin Telli Dizman¹  Ahmet Cagkan Inkaya¹  Alparslan Alp³  Sehnaz Alp¹  Serhat Unal¹ 

[1] Department of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine;Department of Internal Medicine, Hacettepe University Faculty of Medicine;Department of Microbiology and Clinical Microbiology, Hacettepe University Faculty of Medicine

关键词: human coronavirus;    respiratory viruses;    prevalence;    adult population;    COVID-19;   

DOI  :  10.7883/yoken.JJID.2022.255

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

18 years) between January 1, 2015, and January 1, 2020, whose respiratory specimens were tested by multiplex real-time polymerase chain reaction. In total, 7,861 respiratory samples (4,540 patients) were included, 38% of which tested positive for any respiratory virus. Of these, 212 (12.2%) samples were positive for HCoVs, and their co-infection with other respiratory viruses was 30.6%. Rhinovirus (27.6%) was the most common co-infection among all three HCoVs. The overall prevalence of HCoVs tended to be the highest in the winter (40.9%). Patients aged ≥60 years had the highest prevalence of overall HCoVs (39.7%). Given the duration and large sample size, this study from Turkey is one of the largest to date among adults in the literature. These epidemiological data and molecular surveillance of HCoVs have important implications for the control and prevention of respiratory infections.

【 授权许可】

Unknown