Monomicrobial Necrotizing Fasciitis and Sepsis Caused by Pseudomonas aeruginosa and Pseudomonas fluorescens : a Series of Ten Cases

Japanese journal of infectious diseases

article

Jiun-Liang Chen¹  Tsung-Yu Huang²  Liang Tseng Kuo¹  Kuo-Chin Huang¹  Yao-Hung Tsai¹ 

[1]Department of Orthopaedic Surgery, Chiayi Chang Gung Memorial Hospital

[2]College of Medicine, Chang Gung University

[3]Division of Infectious Diseases, Department of Internal Medicine, Chiayi Chang Gung Memorial Hospital

关键词: monomicrobial;    necrotizing fasciitis;    Pseudomonas aeruginosa;    Pseudomonas fluorescens;   

DOI  :  10.7883/yoken.JJID.2022.087

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

Monomicrobial necrotizing fasciitis caused by Pseudomonas species is a rare infection. This study aimed to elucidate the specific characteristics and clinical outcomes of necrotizing fasciitis caused by Pseudomonas aeruginosa and Pseudomonas fluorescens. Ten patients with monomicrobial necrotizing fasciitis caused by Pseudomonas species were retrospectively reviewed in an 8-year period. Differences in mortality, patient characteristics, clinical presentation, laboratory data, and clinical outcomes were compared between the death and survival groups. Two patients died, showing a mortality rate of 20%. P. aeruginosa was the causative agent in nine patients and P. fluorescens in one patient. The most common comorbidity was type 2 diabetes (n = 5). We found that patients who died had lower albumin levels and higher leukocyte counts than those who survived. Monomicrobial necrotizing fasciitis caused by Pseudomonas species needs emergent surgical intervention and aggressive intensive care due to the high mortality rate. We report the first case of monomicrobial necrotizing fasciitis caused by P. fluorescens. Severe hypoalbuminemia and high leukocyte counts in initial laboratory examinations can be considered poor prognostic factors.

【 授权许可】

Unknown