Anti-photoaging Constituents from Eurya emarginata Leaves

Journal of the Korean Chemical Society

article

Sung Chun Kim¹  So Yeon Oh¹  Hyejin Hyeon¹  Boram Go¹  Seon-A Yoon¹  Yong-Hwan Jung¹  Nam Ho Lee²  Young-Min Ham¹ 

[1] Biodiversity Research Institute;Department of Chemistry and Cosmetics, Jeju National University

关键词: Eurya emarginata;    Anti-oxidant;    Anti-photoaging;    Quercitrin;   

DOI  :  10.5012/jkcs.2023.67.2.150

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Eurya emarginata is an evergreen tree growing in the southern regions of Korea including Jeju Island. In thisstudy, antioxidant and anti-photoaging effects were investigated with the extracts of E. emarginata leaves. As comparativestudies with the extract and five solvent fractions, the EtOAc fraction showed the most effective DPPH and ABTS+ radicalscavenging activities. The EtOAc fraction also inhibited matrix metalloproteinase-1 (MMP-1) production most effectively.Phytochemical study on the EtOAC fraction resulted in the isolation of three compounds; eutigoside C (1), eutigoside B (2)and quercitrin (3). Among the isolates (1-3), quercitrin (3) showed excellent antioxidant activities and inhibitory properties onMMP-1 production. Based on these results, it was suggested that extracts of E. emarginata leaves could be developed as natural anti-photoaging agents in cosmetic formulations.

【 授权许可】

Unknown