A survey of bovine leukemia virus resistant bovine leukocyte antigen ( BoLA ) -DRB3*009:02 allele-carrying Japanese Black cattle in two prefectures in Japan

The Journal of Veterinary Medical Science

article

Kosuke NOTSU¹  Yoshinobu INOUE²  Tsuneyuki MASUDA³  Masahiro INOUE²  Shuya MITOMA⁵  Xinyue WU¹  Junzo NORIMINE⁵  Satoshi SEKIGUCHI⁵ 

[1] Graduate School of Medicine and Veterinary Medicine, University of Miyazaki;Tottori Prefectural Livestock Research Center;Faculty of Veterinary Medicine, Okayama University of Science;Seibu Livestock Hygiene Service Center;Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki;Center for Animal Disease Control, University of Miyazaki

关键词: bovine leukemia virus;    bovine leukocyte antigen (BoLA)-DRB3*00902;    breeding;    regional survey;   

DOI  :  10.1292/jvms.22-0285

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

The bovine leukocyte antigen (BoLA) DRB3*009:02 allele is strongly associated with a low/undetectable bovine leukemia virus (BLV) proviral load. Understanding the status of cattle possessing DRB3*009:02 allele is key for BLV control by breeding. We performed a survey of DRB3*009:02-carrying cattle in two prefectures in Japan using a TaqMan assay developed previously. The allele was found in 3.8% (confidence interval (CI): 3.3–4.3) of 6020 Japanese Black female cattle. A prefecture-level difference was found: the allele was observed in 8.6% CI: 7.5–9.9) of 2242 cattle of the birth prefecture B in Kyushu/Okinawa region, and this percentage was significantly higher than those of prefecture C in Kyushu/Okinawa region (1.3% (CI: 0.4–3.4) of 319) and prefecture A in Chugoku region (0.9% (CI: 0.6–1.4) of 2741), respectively. Consideration on the difference in possession of DRB3*009:02 allele is needed to establish the more efficient control strategy of BLV infection in Japanese Black cattle.

【 授权许可】

Unknown