A Dosimetric Comparison of 7 Field IMRT, 9 Field IMRT, VMAT and 3-D Conformal Radiotherapy for the Treatment of Localized Intermediate Risk Prostate Cancer.

International Journal of Hematology and Oncology

article

Kemal EKICI¹  Mehmet KULOGLU¹  Aysun Ozsoy ATA²  Ozcan ATAHAN³  Osman TIRYAKIOGLU⁴ 

[1] Istinye University, Medical Faculty, VM Medical Park Hospital, Department of Radiation Oncology;Samatya Research and Training Hospital, Department of Radiation Oncology;Istinye University, Medical Faculty, VM Medical Park Hospital, Department of Urology;Istinye University, Medical Faculty, VM Medical Park Hospital, Department of Department of Cardiovascular Surgery

关键词: Prostate cancer;    Radiotherapy;    Dosimetric comparison;    Treatment planning;   

DOI  :  10.4999/uhod.226166

学科分类：肿瘤学

来源: International Journal of Hematology and Oncology

【 摘 要 】

The objective of this study was to invastigate the potential role of various radiotherapy planning methods for localised intermediate risk prostate cancer. We compare Linac-based 7 field intensity modulated radiation therapy (IMRT), 9 field IMRT, volumetric modulated arc therapy (VMAT) and 3-D conformal radiotherapy (3D-CRT) techniques for localised prostate cancer. Forty plans with localised prostate cancer treated at our institution were randomly selected for this study. Ten radiotherapy treatment plans have been created for all 10 patients, including 7 field IMRT, 9 field IMRT, VMAT and 3D-CRT. All plans were designed to deliver 76 Gy in 38 fractions to the planning target volume (PTV). The HI and CI for 7-IMRT, 9-IMRT and VMAT modalities were better than 3D-CRT. For the CI, VMAT was better than 9-IMRT and 3D-CRT, but no significant difference was found with 7-IMRT modality. PTVDmax was found to be lower in 3D-CRT compared to other three treatment methods. VMAT was better than 3D-CRT in femoral head V30, but there was no difference between other modalities. In the number of monitor units(MU) 3D-CRT was found to be lower than the other modalities, in VMAT the number of MU’s was found to be lower than 7 and 9-IMRT modalities. It was observed that the three IMRT modalities studied showed superior target coverage with less variation between each plan in comparison to 3D-CRT. VMAT treatment duration and femoral head V30 dose were superior to IMRT techniques.

【 授权许可】

Unknown