Exocytosis, endocytosis and recycling of secretory vesicles in neuroendocrine cells, and its regulation by cortical actin

Biocell

article

ANA M. CÁRDENAS¹  LUCIANA I. GALLO²  FERNANDO D. MARENGO² 

[1] Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso;Instituto de Fisiología, Biología Molecular y Neurociencias, CONICET. Departamento de Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires

关键词: Cortical actin;    Neuroendocrine cell;    Chromaffin cell;    Exocytosis;    Endocytosis;   

DOI  :  10.32604/biocell.2022.019086

学科分类：仪器

来源: Biocell

【 摘 要 】

The cortical actin network is a mesh of filaments distributed beneath the plasmalemma that dynamically reactsin response to stimuli. This dynamic network of cortical filaments, together with motor myosin partners, adjusts theplasmalemma tension, organizes membrane protein microdomains, remodels the cell surface and drives vesiclemotion in order to fine-tune exocytosis, endocytosis and recycling of secretory vesicles. In this review, we discuss howthese mechanisms work in secretory cells.

【 授权许可】

CC BY