期刊论文详细信息
Engineering H5N1 avian influenza viruses to study human adaptation
Article
关键词: A VIRUSES;    RECEPTOR SPECIFICITY;    MOUSE MODEL;    VIRULENCE DETERMINANTS;    SWINE INFLUENZA;    CLEAVAGE SITE;    TRANSMISSION;    HEMAGGLUTININ;    FERRETS;    REPLICATION;   
DOI  :  10.1038/nature11170
来源: SCIE
【 摘 要 】

Two studies of H5N1 avian influenza viruses that had been genetically engineered to render them transmissible between ferrets have proved highly controversial. Divergent opinions exist about the importance of these studies of influenza transmission and about potential 'dual use' research implications. No consensus has developed yet about how to balance these concerns. After not recommending immediate full publication of earlier, less complete versions of the studies, the United States National Science Advisory Board for Biosecurity subsequently recommended full publication of more complete manuscripts; however, controversy about this and similar research remains.

【 授权许可】

Free   

  文献评价指标  
  下载次数:0次 浏览次数:3次