Emergence and pandemic potential of swine-origin H1N1 influenza virus

Review

关键词: LOWER RESPIRATORY-TRACT;    A H5N1 VIRUS;    MEDIATED ANTIVIRAL RESPONSES;    POLYMERASE SUBUNIT PB2;    SINGLE-AMINO-ACID;    MOLECULAR-BASIS;    HOST-RANGE;    IMMUNOCOMPROMISED CHILD;    RECEPTOR SPECIFICITY;    BACTERIAL PNEUMONIA;   

DOI  :  10.1038/nature08157

来源: SCIE

【 摘 要 】

Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of new strains will continue to pose challenges to public health and the scientific communities. A prime example is the recent emergence of swine-origin H1N1 viruses that have transmitted to and spread among humans, resulting in outbreaks internationally. Efforts to control these outbreaks and real-time monitoring of the evolution of this virus should provide us with invaluable information to direct infectious disease control programmes and to improve understanding of the factors that determine viral pathogenicity and/or transmissibility.

【 授权许可】

Free