Haematopoietic cell transplantation as immunotherapy

Article

关键词: VERSUS-HOST-DISEASE;    ALLOGENEIC BONE-MARROW;    MINOR HISTOCOMPATIBILITY ANTIGENS;    ACUTE MYELOID-LEUKEMIA;    TUMOR GENE WT1;    T-LYMPHOCYTES;    CLASS-I;    HLA SYSTEM;    GRAFT;    PROTEINASE-3;   

DOI  :  10.1038/35077251

来源: SCIE

【 摘 要 】

The graft-versus-tumour effect seen after allogeneic (genetically different) haematopoietic cell transplantation for human malignancies represents the clearest example of the power of the human immune system to eradicate cancer. Recent advances in our understanding of the immunobiology of stem-cell engraftment, tolerance and tumour eradication are allowing clinicians to better harness this powerful effect.

【 授权许可】

Free