A large single-center prospective study to investigate the factors influencing the choice of breast-conserving surgery versus mastectomy in Chinese women with early breast cancer

World Journal of Surgical Oncology

Research

Shuo Zhang¹  Yunjiang Liu¹  Jing Zhang¹  Yue Li²  Huina Han²  Zhensheng Li²  Jun Zhang²  Kaiye Du² 

[1] Department of Breast Surgery, the Fourth Hospital of Hebei Medical University, 050035, Shijiazhuang, China;Department of Radiation Oncology, the Fourth Hospital of Hebei Medical University, 050035, Shijiazhuang, China;

关键词: Early breast cancer;    Breast-conserving surgery;    Mastectomy;    Decision-making;    Chinese;   

DOI  :  10.1186/s12957-023-02924-y

 received in 2022-07-05, accepted in 2023-01-30,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundCompared to mastectomy, breast-conserving surgery (BCS) provides the same survival rate and a higher quality of life for patients with early breast cancer (EBC). However, Chinese women with EBC are known to have a low BCS rate. A large prospective cohort study was conducted to investigate the factors influencing the choice of BCS in this population.MethodsIn 2017, all women with unilateral EBC and eligible for BCS at our institution were enrolled. Before surgery, the patient’s trust in the surgeon and her perceived strength of the surgeon’s recommendation of BCS were measured through an in-person interview and validated ad hoc questionnaire. Multivariate logistic regressions on BCS procedure vs. mastectomy were used to estimate the odds ratio (OR).ResultsOne thousand one hundred thirty-six patients enrolled at analysis had an average age of 51.8 and tumor size of 2.4 cm. 19.9% of patients had BCS. The “strong” level of trust in the surgeon was significantly associated with BCS with an OR of 2.944 (p<0.001) when compared to the “average or under” trust. The “strong” and “moderate” strengths in surgeon recommendation for BCS were also found to be significantly associated with the BCS procedure with ORs of 12.376 (p <0.001) and 1.757 (p =0.040), respectively, compared to the “neutral or dissuaded” strength.ConclusionsStronger trust in surgeons and BCS recommendation by surgeons are associated with a higher rate of BCS in Chinese women with EBC. Interventional trials are needed to confirm this finding.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 1